1,2-Dipalmitoyl-sn-glycerol
(Synonyms: 1,2-双棕榈酸甘油酯,1,2-DPG,NSC 269964) 目录号 : GC13877A diacylglycerol
Cas No.:30334-71-5
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >97.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM.[1] 1,2-Dipalmitoyl-sn-glycerol promotes exponential growth of Frankia Gram-positive bacteria.[2]
Reference:
[1]. Walker, J.M., and Sando, J.J. Activation of protein kinase C by short chain phosphatidylcholines. J. Biol. Chem. 263(10), 4537-4540 (1988).
[2]. Selim, S., and Schwencke, J. 1,2-dipalmitoyl phosphatidylcholine, 1,2-dipalmitoyl phosphatidic acid or 1,2-dipalmitoyl-sn-glycerol inhibit sporangia formation and promote exponential growth of various Frankia isolates from the casuarinaceae family. Soil Biol. Biochem. 26(5), 569-575 (1994).
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.7578 mL | 8.7889 mL | 17.5778 mL |
| 5 mM | 0.3516 mL | 1.7578 mL | 3.5156 mL |
| 10 mM | 0.1758 mL | 0.8789 mL | 1.7578 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。