1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.^1,2 It has been used as a precursor in the synthesis of differently substituted trimers of the group A N. meningitidis capsular polysaccharide repeating unit for use in immunological experiments.² It has also been used in the synthesis of fluorescent probes for lysosomal labeling.³

1.Saxon, E., Luchansky, S.J., Hang, H.C., et al.Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligationJ. Am. Chem. Soc.124(50)14893-14902(2002) 2.SlÄttegÅrd, R., Teodorovic, P., Kinfe, H.H., et al.Synthesis of structures corresponding to the capsular polysaccharide of Neisseria meningitidis group AOrg. Biomol. Chem.3(20)3782-3787(2005) 3.Yapici, N.B., Bi, Y., Li, P., et al.Highly stable and sensitive fluorescent probes (LysoProbes) for lysosomal labeling and trackingSci. Rep.58576(2015)