1-Linoleoyl-d11-2-Linoleoyl-sn-glycero-3-PC
(Synonyms: 1,2-Dilinoleoyl-sn-glycero-3-Phosphocholine-d11,DLPC-d11,18:2 (cis) PC-d11) 目录号 : GC918111-Linoleoyl-d11-2-linoleoyl-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dilinoleoyl-sn-glycero-3-PC by GC- or LC-MS.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
1-Linoleoyl-d11-2-linoleoyl-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dilinoleoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dilinoleoyl-sn-glycero-3-PC is a phospholipid containing the polyunsaturated long-chain (18:2) linoleic acid inserted at the sn-1 and sn-2 positions. It has been used to generate micelles, liposomes, and other types of artificial membranes.1,2,3
References:
[1].Ritter, M., Schmidt, S., Jakab, M., et al.Evidence for the formation of symmetric and asymmetric DLPC-DAPC lipid bilayer domainsCell. Physiol. Biochem.32(1)46-52(2013).
[2].Mazari, A., Iwamoto, S., and Yamauchi, R.Effects of linoleic acid position in phosphatidylcholines and cholesterol addition on their rates of peroxidation in unilamellar liposomesBiosci. Biotechnol. Biochem.74(5)1013-1017(2010).
[3].Bagatolli, L.A., and Gratton, E.A correlation between lipid domain shape and binary phospholipid mixture composition in free standing bilayers: A two-photon fluorescence microscopy studyBiophys. J.79(1)434-447(2000).
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.2607 mL | 6.3036 mL | 12.6072 mL |
| 5 mM | 0.2521 mL | 1.2607 mL | 2.5214 mL |
| 10 mM | 0.1261 mL | 0.6304 mL | 1.2607 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。