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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE

(Synonyms: 1-棕榈-SN-甘油-3-磷酸乙醇胺,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine) 目录号 : GC18651

A lysophospholipid

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE Chemical Structure

Cas No.:53862-35-4

规格 价格 库存
100µg
¥1,380.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE has been used as an internal standard for the quantification of saturated lysophosphoethanolamines. [4]

Reference:
[1]. Nieman, D.C., Shanely, R.A., Gillitt, N.D., et al. Serum metabolic signatures induced by a three-day intensified exercise period persist after 14 h of recovery in runners. J. Proteome Res. 12(10), 4577-4584 (2013).
[2]. Achterberg, V., and Gercken, G. Cytotoxicity of ester and ether lysophospholipids on Leishmania donovani promastigotes. Mol. Biochem. Parasitol. 23(2), 117-122 (1987).
[3]. Li, S., Liu, H., Jin, Y., et al. Metabolomics study of alcohol-induced liver injury and hepatocellular carcinoma xenografts in mice. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879(24), 2369-2375 (2011).
[4]. Avadhani, M., Geyer, R., White, D.C., et al. Lysophosphatidylethanolamine is a substrate for the short-chain alcohol dehydrogenase SocA from Myxococcus xanthus. J. Bacteriol. 188(24), 8543-8550 (2006).

Chemical Properties

Cas No. 53862-35-4 SDF
别名 1-棕榈-SN-甘油-3-磷酸乙醇胺,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine
化学名 hexadecanoic acid, (2R)-3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester
Canonical SMILES O[C@@H](COP(OCC[NH3+])([O-])=O)COC(CCCCCCCCCCCCCCC)=O
分子式 C21H44NO7P 分子量 453.6
溶解度 Soluble in DMSO, DMF ,Chloroform 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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1 mM 2.2046 mL 11.0229 mL 22.0459 mL
5 mM 0.4409 mL 2.2046 mL 4.4092 mL
10 mM 0.2205 mL 1.1023 mL 2.2046 mL
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