1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol
(Synonyms: Glycerol Tripalmitate-d9, TG(16:0-d9/16:0/16:0), Tripalmitin-d9, 1,2,3-Tripalmitoyl-sn-glycerol-d9, Tripalmitoylglycerol-d9) 目录号 : GC90312一种用于量化1,2,3-三棕榈酰-rac-甘油的内部标准。
Cas No.:2738376-70-8
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
1-Palmitoyl-d9-2,3-dipalmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2,3-tripalmitoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Tripalmitoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1, sn-2, and sn-3 positions and has been found in palm oil.1 It inhibits glucose-stimulated insulin secretion and reduces viability of INS1 cells in a concentration-dependent manner.2 Myocardial levels of 1,2,3-tripalmitoyl-rac-glycerol are elevated by greater than 5-fold in a rat model of diabetes induced by streptozotocin .3 1,2,3-Tripalmitoyl-rac-glycerol has been used to form the lipid matrices of etoposide-incorporated nanoparticles.4 Formulations containing 1,2,3-tripalmitoyl-rac-glycerol have been used in cosmetic products as thickening and skin-conditioning agents.5
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 1.2249 mL | 6.1244 mL | 12.2489 mL |
5 mM | 0.245 mL | 1.2249 mL | 2.4498 mL |
10 mM | 0.1225 mL | 0.6124 mL | 1.2249 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。