10,13-epoxy-11-methyl-Octadecadienoic Acid
(Synonyms: F2 Furan Fatty Acid, 3-methyl-5-pentyl-2-Furannonanoic Acid, 9M5) 目录号 : GC48782
A furan fatty acid
Cas No.:57818-39-0
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
10,13-epoxy-11-methyl-Octadecadienoic acid is a furan fatty acid.1,2,3,4,5 It prevents the formation of primary and secondary lipid oxidation products during the storage of ω-3 PUFA-enriched fish oil when used at concentrations of 50, 100, and 250 µM.1 10,13-epoxy-11-methyl-Octadecadienoic acid (20 µM) induces transcriptional activation of peroxisome proliferator-activated receptor γ (PPARγ) in a reporter assay.2 It increases lipid accumulation during the differentiation of 3T3-L1 preadipocytes to adipocytes when used at a concentration of 10 µM. 10,13-epoxy-11-methyl-Octadecadienoic acid has been found in marine bacteria, Adriatic fish, and butter.3,4,5
1.Buscato, M.H.H., MÜller, F., Vetter, W., et al.Furan fatty acids in enriched ω-3 fish oil: Oxidation kinetics with and without added monomethyl furan fatty acid as potential natural antioxidantFood Chem.327127087(2020) 2.Lauvai, J., Becker, A.-K., Lehnert, K., et al.The furan fatty acid 9M5 acts as a partial ligand to peroxisome proliferator-activated receptor gamma and enhances adipogenesis in 3T3-L1 preadipocytesLipids54277-288(2019) 3.Shirasaka, N., Nishi, K., and Shimizu, S.Occurrence of a furan fatty acid in marine bacteriaBiochimica et Biophysica Acta1258225-227(1995) 4.Pacetti, D., Alberti, F., Boselli, E., et al.Characterisation of furan fatty acids in Adriatic fishFood Chemistry122(1)209-215(2010) 5.Wendlinger, C., and Vetter, W.High concentrations of furan fatty acids in organic butter samples from the German marketJ. Agric. Food Chem.62(34)8740-8744(2014)
| Cas No. | 57818-39-0 | SDF | |
| 别名 | F2 Furan Fatty Acid, 3-methyl-5-pentyl-2-Furannonanoic Acid, 9M5 | ||
| Canonical SMILES | CCCCCC1=CC(C)=C(CCCCCCCCC(O)=O)O1 | ||
| 分子式 | C19H32O3 | 分子量 | 308.5 |
| 溶解度 | DMSO: slightly soluble,Methanol: slightly soluble | 储存条件 | -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.2415 mL | 16.2075 mL | 32.4149 mL |
| 5 mM | 0.6483 mL | 3.2415 mL | 6.483 mL |
| 10 mM | 0.3241 mL | 1.6207 mL | 3.2415 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。