(-)-11-hydroxy-δ8-THC-d3 (exempt preparation)
(Synonyms: (-)-11-hydroxy-δ8-Tetrahydrocannabinol-d3,(-)-trans-δ8-THC-d3,7-hydroxy-δ6-THC-d3) 目录号 : GC91736(−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ8-THC by GC- or LC-MS.
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
(−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ8-THC by GC- or LC-MS. (−)-11-hydroxy-Δ8-THC is categorized as a phytocannabinoid metabolite.[1],[2] (–)-11-hydroxy-Δ8-THC is a metabolite of Δ8-THC . It has analgesic activity in mice. (–)-11-hydroxy-Δ8-THC-d3 is regulated as a Schedule I compound in the United States. (−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
References:
[1].Watanabe, K., Yamamoto, I., Oguri, K., et al.Comparison in mice of pharmacological effects of Δ8-tetrahydrocannabinol and its metabolites oxidized at 11-positionEur. J. Pharm.63(1)1-6(1980).
[2].Rhee, M.H., Vogel, Z., Barg, J., et al.Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclaseJ. Med. Chem.40(20)3228-3233(1997).
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 2.9985 mL | 14.9925 mL | 29.985 mL |
5 mM | 0.5997 mL | 2.9985 mL | 5.997 mL |
10 mM | 0.2999 mL | 1.4993 mL | 2.9985 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。