(-)-11-hydroxy-δ8-THC-d3 (exempt preparation)
(Synonyms: (-)-11-hydroxy-δ8-Tetrahydrocannabinol-d3,(-)-trans-δ8-THC-d3,7-hydroxy-δ6-THC-d3) 目录号 : GC91736(−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ8-THC by GC- or LC-MS.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
(−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ8-THC by GC- or LC-MS. (−)-11-hydroxy-Δ8-THC is categorized as a phytocannabinoid metabolite.[1],[2] (–)-11-hydroxy-Δ8-THC is a metabolite of Δ8-THC . It has analgesic activity in mice. (–)-11-hydroxy-Δ8-THC-d3 is regulated as a Schedule I compound in the United States. (−)-11-hydroxy-Δ8-THC-d3 (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
References:
[1].Watanabe, K., Yamamoto, I., Oguri, K., et al.Comparison in mice of pharmacological effects of Δ8-tetrahydrocannabinol and its metabolites oxidized at 11-positionEur. J. Pharm.63(1)1-6(1980).
[2].Rhee, M.H., Vogel, Z., Barg, J., et al.Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclaseJ. Med. Chem.40(20)3228-3233(1997).
| Cas No. | N/A | SDF | Download SDF |
| 别名 | (-)-11-hydroxy-δ8-Tetrahydrocannabinol-d3,(-)-trans-δ8-THC-d3,7-hydroxy-δ6-THC-d3 | ||
| 分子式 | C21H27D3O3 | 分子量 | 333.5 |
| 溶解度 | N/A | 储存条件 | -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 2.9985 mL | 14.9925 mL | 29.985 mL |
| 5 mM | 0.5997 mL | 2.9985 mL | 5.997 mL |
| 10 mM | 0.2999 mL | 1.4993 mL | 2.9985 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。