(-)-11-hydroxy-δ9-THC
(Synonyms: (-)-7-hydroxy-δ1-Tetrahydrocannabinol,(-)-11-hydroxy-δ9-Tetrahydrocannabinol,(-)-7-hydroxy-δ1-THC) 目录号 : GC91644(–)-11-hydroxy-Δ9-THC is an analytical reference standard categorized as a phytocannabinoid metabolite.
Cas No.:36557-05-8
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
(–)-11-hydroxy-Δ9-THC is an analytical reference standard categorized as a phytocannabinoid metabolite.1,2,3,4 (–)-11-hydroxy-Δ9-THC is a metabolite of Δ9-THC . (–)-11-hydroxy-Δ9-THC is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
References:
[1].Martin, B.R., Balster, R.L., Razdan, R.K., et al.Behavioral comparisons of the stereoisomers of tetrahydrocannabinolsLife Sci.29(6)565-574(1981).
[2].Grafinger, K.E., and Weinmann, W.Determination of the cross-reactivity of the biological metabolite (-)-trans-Δ9-tetrahydrocannabinol-carboxylic acid-glucuronide (THC-COOH-Gluc) for cannabinoid immunoassaysJ. Anal. Toxicol.45(3)291-296(2021).
[3].Bland, T.M., Haining, R.L., Tracy, T.S., et al.CYP2C-catalyzed delta(9)-tetrahydrocannabinol metabolism: Kinetics, pharmacogenetics and interaction with phenytoinBiochem. Pharmacol.70(7)1096-1103(2005).
[4].Coles, R., Clements, T.T., Nelson, G.J., et al.Simultaneous analysis of the Δ9-THC metabolites 11-nor-9-carboxy-Δ9-THC and 11-hydroxy-Δ9-THC in meconium by GC-MSJ. Anal. Toxicol.29(6)522-527(2016).
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.0257 mL | 15.1286 mL | 30.2572 mL |
| 5 mM | 0.6051 mL | 3.0257 mL | 6.0514 mL |
| 10 mM | 0.3026 mL | 1.5129 mL | 3.0257 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。