12-methyl Tridecanoic Acid
(Synonyms: 12-甲基十三烷酸) 目录号 : GC49808A methylated fatty acid
Cas No.:2724-57-4
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
12-methyl Tridecanoic acid is a methylated fatty acid that has been found in bovine milk.1 Topical ocular application of 12-methyl tridecanoic acid (200 µM) decreases angiogenesis and corneal opacity in mouse models of alkali- or P. aeruginosa-induced eye injury.2
1.Ran-Ressler, R.R., Sim, D., O’Donnell-Megaro, A.M., et al.Branched chain fatty acid content of United States retail cow’s milk and implications for dietary intakeLipids46(7)569-576(2011) 2.Cole, N., Hume, E.B.H., Jalbert, I., et al.Effects of topical administration of 12-methyl tetradecanoic acid (12-MTA) on the development of corneal angiogenesisAngiogenesis10(1)47-54(2007)
| Cas No. | 2724-57-4 | SDF | Download SDF |
| 别名 | 12-甲基十三烷酸 | ||
| Canonical SMILES | CC(C)CCCCCCCCCCC(O)=O | ||
| 分子式 | C14H28O2 | 分子量 | 228.4 |
| 溶解度 | DMSO: soluble | 储存条件 | -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.3783 mL | 21.8914 mL | 43.7828 mL |
| 5 mM | 0.8757 mL | 4.3783 mL | 8.7566 mL |
| 10 mM | 0.4378 mL | 2.1891 mL | 4.3783 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Characterization of a new antibiotic of iturin group: bacillomycin D
J Antibiot (Tokyo) 1980 Oct;33(10):1146-9.PMID:7451365DOI:10.7164/antibiotics.33.1146.
The characterization of an antibiotic isolated from a strain of Bacillus subtilis revealed that this compound is a new antifungal antibiotic of the iturin group. It contains a lipid moiety which is a mixture of 3-amino 12-methyl Tridecanoic Acid (40%) and 3-amino 12-methyl tetradecanoic acid (60%) and a peptide moiety: L-Asp1, D-Asp1, L-Glu1, L-Pro1, D-Ser1, L-Thr1 and D-Tyr1. These two moieties are joined by a threonyl-beta-aminoacid linkage.