2', 3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate)
目录号 : GN201902',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination.
Sample solution is provided at 25 µL, 10mM.
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2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddTTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
| purity | ≥90% by AX-HPLC | Extinction Coefficient | 9,650 Lmol-1cm-1 at 267 nm |
| 分子式 | C10H17N2O12P3S (free acid) | 分子量 | 482.20 g/mole (free acid) |
| Salt Form | Li+ | Concentration | 100 mM |
| Buffer | H2O | 储存条件 | -20°C or below |
| Synonyms | Alpha Thiol ddTTP | Backbone | 5'-O-(1-Thiotriphosphate) |
| Base Analog | Thymidine | Sugar Type | 3'-Deoxy |
| Nucleotide Category | Phosphate Modified |