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2,4-Diacetylphloroglucinol

(Synonyms: 2,4-二乙酰基间苯三酚,5-Acetyl-2,4,6-trihydroxyacetophenone,DAPG,1,3-Diacetyl-2,4,6-trihydroxybenzene) 目录号 : GC14471

A broad spectrum antibiotic used to control plant diseases

2,4-Diacetylphloroglucinol Chemical Structure

Cas No.:2161-86-6

规格 价格 库存 购买数量
10mg
¥392.00
现货
50mg
¥1,722.00
现货
100mg
¥2,856.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

2,4-Diacetylphloroglucinol is an agent against various plant pathogenic fungi, viruses, bacteria, and nematodes.

2,4-Diacetylphloroglucinol, a non-nitrogen-containing compound produced by some isolates of P. fluorescens, has been used to increase crop yield by controlling plant root diseases.

In vitro: A previous study was conducted to determine if 2,4-diacetylphloroglucinol was toxic to selected nematodes. The plant-parasitic nematodes including Pratylenchus scribneri and Xiphinema americanum, Heterodera glycines, Meloidogyne incognita, and the bacterial-feeding nematodes such as Pristionchus pacificus, Caenorhabditis elegans, and Rhabditis rainai, were found to be immersed in concentrations ranging from 0 to 100 μg/ml of 2,4-diacetylphloroglucinol. Moreove, the egg hatch and viability of juveniles and adults were determined, and the results showed that 2,4-diacetylphloroglucinol was toxic to X. americanum adults with an LD50 of 8.3 μg/ml. 2,4-Diacetylphloroglucinol could decrease M. incognita egg hatch, but stimulated C. elegans hatch. Whereas, the viability of M. incognita J2 and of C. elegans J1 and adults was not affected. There were no observed effects on the other nematodes. These findings indicated that 2,4-diacetylphloroglucinol was not toxic to all nematodes, and did not affect the tested species of beneficial bacterial-feeding nematodes [1].

In vivo: Up to now, there is no animal in vivo data reported.

Clinical trial: So far, no clinical study has been conducted.

Reference:
[1] Meyer, S. L.F.,Halbrendt, J.M.,Carta, L.K., et al. Toxicity of 2,4-diacetylphloroglucinol (DAPG) to plant-parasitic and bacterial-feeding nematodes. Journal of Nematology 41(4), 274-280 (2009).

Chemical Properties

Cas No. 2161-86-6 SDF
别名 2,4-二乙酰基间苯三酚,5-Acetyl-2,4,6-trihydroxyacetophenone,DAPG,1,3-Diacetyl-2,4,6-trihydroxybenzene
化学名 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-ethanone
Canonical SMILES OC1=C(C(C)=O)C(O)=C(C(C)=O)C(O)=C1
分子式 C10H10O5 分子量 210.2
溶解度 ≥ 11.55mg/mL in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 4.7574 mL 23.7869 mL 47.5737 mL
5 mM 0.9515 mL 4.7574 mL 9.5147 mL
10 mM 0.4757 mL 2.3787 mL 4.7574 mL
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