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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Sale

目录号 : GC30561

2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂,可以在压力引起的溃疡大鼠中,维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Chemical Structure

Cas No.:137089-36-2

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1mg
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5mg
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10mg
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Sample solution is provided at 25 µL, 10mM.

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产品描述

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1].

[1]. Kohda I, et al. Further studies on the anti-ulcerogenic effects of compound, 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide. Chem Pharm Bull (Tokyo). 1991 Jul;39(7):1832-6.

Chemical Properties

Cas No. 137089-36-2 SDF
Canonical SMILES CCCCCCC/C=C/C(NCCSCCC1CCCCC1)=O
分子式 C20H37NOS 分子量 339.58
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.9448 mL 14.7241 mL 29.4481 mL
5 mM 0.589 mL 2.9448 mL 5.8896 mL
10 mM 0.2945 mL 1.4724 mL 2.9448 mL
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