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2-O-methyl PAF C-18 (hydrate) Sale

(Synonyms: Edelfosine, ET-18-OCH3, 1Ooctadecyl2Omethylsnglyceryl3phosphorylcholine) 目录号 : GC48450

A synthetic PAF analog

2-O-methyl PAF C-18 (hydrate) Chemical Structure

规格 价格 库存 购买数量
5mg
¥720.00
现货
10mg
¥1,371.00
现货
50mg
¥5,756.00
现货
100mg
¥9,782.00
现货

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Sample solution is provided at 25 µL, 10mM.

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2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.1 In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.2

1.van Blitterswijk, W.J., Hilkmann, H., and Storme, G.A.Accumulation of an alkyl lysophospholipid in tumor cell membranes affects membrane fluidity and tumor cell invasionLipids22(11)820-823(1987) 2.Cardile, V., Jiang, X., Renis, M., et al.Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero-3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytesBrain Research715(1-2)98-103(1996)

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.9095 mL 9.5475 mL 19.0949 mL
5 mM 0.3819 mL 1.9095 mL 3.819 mL
10 mM 0.1909 mL 0.9547 mL 1.9095 mL
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