2C-T (hydrochloride)
(Synonyms: 2,5-Dimethoxy-4-methylthiophenethylamine) 目录号 : GC42145An Analytical Reference Standard
Cas No.:61638-10-6
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects.[1][2] The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances. [3][4] 2C-T (hydrochloride) is described formally as 2,5-dimethoxy-4-methylthiophenylethylamine hydrochloride. It has structural and pharmacokinetic properties similar to the drugs mescaline (hydrochloride) and 2C-T-2 (hydrochloride) . [5] This product is intended for forensic and research purposes.
Reference:
[1]. Bruno, R., Matthews, A.J., Dunn, M., et al. Emerging psychoactive substance use among regular ecstasy users in Australia. Drug Alcohol Depend. 124(1-2), 19-25 (2012).
[2]. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. Journal of Pharmacology and Experimental Therapeutics 321, 1054-1061 (2007).
[3]. Meyer, M.R., and Maurer, H.H. Metabolism of designer drugs of abuse: An updated review. Curr. Drug Metab. 11(5), 468-482 (2010).
[4]. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).
[5]. Nichols, D.E., and Shulgin, A.T. Sulfur analogs of psychotomimetic amines. Journal of Pharmaceutical Sciences 65(10), 1554-1556 (1976).
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.7908 mL | 18.9538 mL | 37.9075 mL |
| 5 mM | 0.7582 mL | 3.7908 mL | 7.5815 mL |
| 10 mM | 0.3791 mL | 1.8954 mL | 3.7908 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。