3,4-DMMA (hydrochloride)
(Synonyms: 3,4-Dimethoxymethamphetamine) 目录号 : GC42212An Analytical Reference Standard
Cas No.:70932-18-2
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >97.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
3,4-Dimethoxymethamphetamine (3,4-DMMA) (hydrochloride) is an analog of 3,4-methylenedioxymethamphetamine (MDMA), a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. DMMA appears to interfere with monoamine transport, inhibiting uptake of noradrenalin and serotonin transporters (Kis = 22.8 and 7.7 μM, IC50s = 253.4 and 108 μM, respectively). [1] DMMA is significantly less potent than MDMA (Kis = 0.6 and 2.5 μM; IC50s = 6.6 and 34.8 μM for MDMA inhibition of noradrenalin and serotonin transporters, respectively).[1]
Reference:
[1]. Montgomery, T., Buon, C., Eibauer, S., et al. Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines. British Journal of Pharmacology 152, 1121-1130 (2007).
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 4.07 mL | 20.35 mL | 40.7 mL |
| 5 mM | 0.814 mL | 4.07 mL | 8.14 mL |
| 10 mM | 0.407 mL | 2.035 mL | 4.07 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。