3-hydroxy Heptadecanoic Acid
(Synonyms: β-hydroxy Heptadecanoic Acid, 3-hydroxy Heptadecylic Acid, 3-hydroxy Margaric Acid) 目录号 : GC45774
A hydroxy fatty acid
Cas No.:40165-89-7
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
3-hydroxy Heptadecanoic acid is a hydroxylated fatty acid. It is a component of LPS in several species of Gram-negative bacteria.1,2 Levels of 3-hydroxy heptadecanoic acid are decreased in the feces of patients with Crohn's disease.
|1. Weintraub, A., Larsson, B.E., and Lindberg, A.A. Chemical and immunochemical analyses of Bacteroides fragilis lipopolysaccharides. Infect. Immun. 49(1), 197-201 (1985).|2. Uhlig, S., Neg•rd, M., Heldal, K.K., et al. Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry. J. Chromatogr. A 1434, 119-236 (2016).|3. De La Cochetiere, M.F., Rouge, C., Szponar, B., et al. 3-Hydroxy fatty acids in faeces of patients with Crohn's disease or ulcerative colitis as a non-invasive diagnostic approach. Microb. Ecol. Health Dis. 19(1), 1-6 (2007).
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.4904 mL | 17.452 mL | 34.904 mL |
| 5 mM | 0.6981 mL | 3.4904 mL | 6.9808 mL |
| 10 mM | 0.349 mL | 1.7452 mL | 3.4904 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。