3-Hydroxydodecanoic acid
(Synonyms: 3-羟基月桂酸) 目录号 : GC30642
A hydroxy fatty acid
Cas No.:1883-13-2
Sample solution is provided at 25 µL, 10mM.
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3-hydroxy Lauric acid is a hydroxylated fatty acid that is found in bacteria as well as Pseudosuberites and D. calyx sea sponges.1,2,3,4 It has antifungal activity against a panel of seven fungi (MICs = 10-50 μg/ml).3 3-hydroxy Lauric acid acts as a partial agonist of GPR84 receptors in vitro (EC50 = 5.24 μM).5 [Matreya, LLC. Catalog No. 1731]
1.Kim, M.C., Pak, S.H., Rim, S.G., et al.Luteolibacter arcticus sp. nov., isolated from high Arctic tundra soil, and emended description of the genus LuteolibacterInt. J. Syst. Evol. Microbiol.65(Pt. 6)1922-1928(2015) 2.Panda, S., Bandyopadhyay, P.K., and Chatterjee, S.N.Characterization of Pseudomonas aeruginosa PB112 (JN996498) isolated from infected Labeo bata (Hamilton) by 16S rRNA gene sequence analysis and fatty acid methyl ester (FAME) analysisAfrican J. Biotechnol.12(4)400-405(2013) 3.He, R., Wakimoto, T., Egami, Y., et al.Heterologously expressed β-hydroxyl fatty acids from a metagenomic library of a marine spongeBioorg. Med. Chem. Lett.22(24)7322-7325(2012) 4.Barnathan, G., Kornprobst, J.-M., Doumenq, P., et al.Sponge fatty acids, 5. Characterization of complete series of 2-hydroxy long-chain fatty acids in phospholipids of two Senegalese marine sponges from the family suberitidae: Pseudosuberites sp. and Suberites massaJ. Nat. Prod.56(12)2104-2113(2004) 5.Kaspersen, M.H., Jenkins, L., Dunlop, J., et al.Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4, and GPR84Med. Chem. Commun.8(6)1360-1365(2017)
| Cas No. | 1883-13-2 | SDF | |
| 别名 | 3-羟基月桂酸 | ||
| Canonical SMILES | CCCCCCCCCC(O)CC(O)=O | ||
| 分子式 | C12H24O3 | 分子量 | 216.32 |
| 溶解度 | DMSO : 100 mg/mL (462.28 mM; Need ultrasonic) | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.6228 mL | 23.1139 mL | 46.2278 mL |
| 5 mM | 0.9246 mL | 4.6228 mL | 9.2456 mL |
| 10 mM | 0.4623 mL | 2.3114 mL | 4.6228 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet