4-Aminobenzaldehyde
(Synonyms: 对氨基苯甲醛; p-aminobenzaldehyde) 目录号 : GC61657
4-Aminobenzaldehyde(p-aminobenzaldehyde)是一种有用的合成试剂和单体，可用于合成单偶氮染料和可光固化的离子交换树脂。4-Aminobenzaldehyde还是金属的腐蚀抑制剂。
Cas No.:556-18-3
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
4-Aminobenzaldehyde (p-aminobenzaldehyde) is a useful synthetic reagent and monomer that can be used to synthesize monoazo dyes and photocurable ion exchange resins. 4-Aminobenzaldehyde is also a corrosion inhibitor of metals[1].
[1]. Paul L, et, al. Organically Functionalized Mesoporous SBA-15 Type Material Bearing Fluorescent Sites for Selective Detection of Hg II from Aqueous Medium. ACS Omega. 2019 Oct 14;4(18):17857-17863.
| Cas No. | 556-18-3 | SDF | |
| 别名 | 对氨基苯甲醛; p-aminobenzaldehyde | ||
| Canonical SMILES | O=CC1=CC=C(N)C=C1 | ||
| 分子式 | C7H7NO | 分子量 | 121.14 |
| 溶解度 | DMSO : 1.96 mg/mL (16.18 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 80°C) | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 8.2549 mL | 41.2746 mL | 82.5491 mL |
| 5 mM | 1.651 mL | 8.2549 mL | 16.5098 mL |
| 10 mM | 0.8255 mL | 4.1275 mL | 8.2549 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Tuning the lattice parameters and porosity of 2D imine covalent organic frameworks by chemically integrating 4-Aminobenzaldehyde as a bifunctional linker
Chem Commun (Camb) 2022 Nov 17;58(92):12875-12878.PMID:36321502DOI:10.1039/d2cc05211c.
As the available building blocks are limited, improving the structural complexity of covalent organic frameworks (COFs) is still challenging. In this work, a new three-component COF synthesis strategy is established by using 4-Aminobenzaldehyde as the bifunctional linker. The lattice parameters, crystallinity, and porosity of these COFs can be efficiently tuned by varying the amount of this linker. This work provides a new way to expand the structural diversity and complexity of imine-linked COFs.
ElNFS1, a nitroreductase gene from Enterobacter ludwigii, confers enhanced detoxification and phytoremediation of 4-nitrobenzaldehyde in rice
Environ Pollut 2022 Dec 1;314:120292.PMID:36181935DOI:10.1016/j.envpol.2022.120292.
4-nitrobenzaldehyde (4-NBA) is a widely used chemical intermediate for industrial application and an important photodegradation product of chloramphenicol. This compound represents a substantial threat to human health and ecosystem due to its genotoxic and mutagenic effect. In this study, the 4-NBA detoxification by transgenic rice overexpressing a bacterial nitroreductase gene, ElNFS1, from Enterobacter ludwigii were investigated. The cytosol-targeted ElNFS1 transgenic plants were selected to comprehensively examine their physio-biochemical responses and phytoremediation potential to 4-NBA. Our results showed that the transgenic plants exhibited strong tolerance to 4-NBA. Overexpression of ElNFS1 could significantly alleviate 4-NBA-induced damages of photosynthetic apparatus and reactive oxygen species overproduction in transgenic plants. The phytoremediation assay revealed that transgenic plants could remove more 4-NBA from the medium than wild-type plants. HPLC and LC-MS assays showed that 4-Aminobenzaldehyde was found in the reductive products of 4-NBA. Altogether, the function of ElNFS1 during 4-NBA detoxification was characterized for the first time, which provides a strong theoretical support for the application potential of ElNFS1 transgenic plants on the phytoremediation of 4-NBA.
Novel cellulose-based halochromic test strips for naked-eye detection of alkaline vapors and analytes
Talanta 2017 Aug 1;170:137-145.PMID:28501149DOI:10.1016/j.talanta.2017.04.002.
A simple, portable and highly sensitive naked-eye test strip is successfully prepared for optical detection of gaseous and aqueous alkaline analytes. Novel pH-sensory tricyanofuran-hydrazone (TCFH) disperse colorant containing a hydrazone recognition functional moiety is successfully synthesized via azo-coupling reaction between active methyl-containing tricyanofuran (TCF) heterocycle and diazonium salt of 4-Aminobenzaldehyde followed by Knoevenagel condensation with malononitrile. UV-vis absorption spectra display solvatochromism and reversible color changes of the TCFH solution in dimethyl sulfoxide in response to pH variations. We investigate the preparation of hydrophobic cellulose/polyethylene terephthalate composites characterized by their high affinity for disperse dyes. Composite films made from CA, Cell/CA, PET/CA, and Cell/PET-CA are produced via solvent-casting procedure using 10-30% modified cellulose or modified polyethylene terephthalate. The mechanical properties and morphologies of these composite films are investigated. The prepared pH-sensory hydrazone-based disperse dye is then applied to dye the produced cellulose-based composite films employing the high temperature pressure dyeing procedure. The produced halochromic PET-CA-TCFH test strip provide an instant visible signal from orange to purple upon exposure to alkaline conditions as proved by the coloration measurements. The sensor strip exhibits high sensitivity and quick detection toward ammonia in both of aqueous and vapor phases by naked-eye observations at room temperature and atmospheric pressure.
Probing the role of surface energetics of electrons and their accumulation in photoreduction processes on TiO₂
Chemistry 2014 Jun 16;20(25):7759-65.PMID:24829086DOI:10.1002/chem.201402039.
We address the role of the energetics of photogenerated electrons in the reduction of 4-nitrobenzaldehyde on TiO2. This model molecule bears two functional groups featuring different reducibilities. Electrochemistry shows that reduction to 4-aminobenzyl alcohol occurs in entirely distinct potential ranges. Partial reduction of the -NO2 group, affording 4-Aminobenzaldehyde, takes place through surface states at potentials positive of the flatband potential (E(fb)). Dark currents caused by reduction of the aldehyde group are observed only at potentials more negative than E(fb), and the process requires an electron accumulation regime. Photocatalysis with TiO2 suspensions agrees with the electrochemical data. In particular, reduction of the nitro group is a relatively fast process (k=0.059 s(-1)), whereas that of the aldehyde group is slower (k=0.001 s(-1)) and requires electron photoaccumulation. Control of the photogenerated charge is a prospective means for achieving chemoselective reductions.
Development of a Sensitive and Selective Method for the Determination of some Selected Aldehydes Based on Fluorescence Quenching
J Fluoresc 2023 Apr 3.PMID:37010648DOI:10.1007/s10895-023-03219-x.
Phenanthrene fluorescence quenching in anionic micellar system of sodium dodecyl sulphate (SDS) was explored for the development of a sensitive and selective method for a group of selected aldehydes (2,6-dichlorobenzaldehyde, 4-(dimethylamino)benzaldehyde, 4-Aminobenzaldehyde, 4-nitrobenzaldehyde, 2-chlorobenzaldehyde, benzaldehyde and 2-methoxybenzaldehyde). Experiments were performed in 0.02 mol L- 1 SDS. All the studied aldehydes quenched the fluorescence intensity of the probe (phenanthrene). Stern-Volmer equation was useful in explaining the phenanthrene quenching by the studied aldehydes. Stern-Volmer constants ([Formula: see text]) were obtained as a result of using the Stern-Volmer equation that gives the information in respect of sensitivity of the method for the studied aldehydes. Greater the [Formula: see text] higher will be the sensitivity and vice versa. [Formula: see text], detection limit (DL) and quantification limit (QL) were observed in the order 2,6-dichlorobenzaldehyde > 4-dimethylaminobenzaldehyde > 4-Aminobenzaldehyde > 4-nitrobenzaldehyde > 2-chlorobenzaldehyde > benzaldehyde > 2-methoxybenzaldehyde. Phenanthrene fluorescence quenching by the studied aldehydes is useful for their determination in environmental samples.