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4-Hydroxybenzoic acid Sale

(Synonyms: 对羟基苯甲酸) 目录号 : GC11270

A phenolic acid

4-Hydroxybenzoic acid Chemical Structure

Cas No.:99-96-7

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500mg
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产品描述

4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

Most of the gram-positive and some gram-negative bacteria are sensitive to trans 4-Hydroxycinnamic acid (4-HBA) and 4-Hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 μg/mL, respectively. The antimicrobial activities of 4-Hydroxycinnamic acid and t4-HCA against 11 food pathogenic bacteria, 6 plant pathogenic bacteria, 2 yeasts and 15 plant pathogenic fungi are tested by the paper disc method. These compounds inhibit the growth of most of the bacteria and yeasts at concentrations of 200-400 μg. However, the inhibition is more effective against most of the gram-positive bacteria. When tested by the paper disc method, 4-Hydroxycinnamic acid has stronger antimicrobial activity than t4-HCA against S. aureus, L. mesenteroides, S. cerevisiae and C. albicans at a concentration of 50 μg. However, no inhibitory effect against fungi was observed at concentrations even up to 1000 μg[1].

References:
[1]. Cho JY, Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull. Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6.

Chemical Properties

Cas No. 99-96-7 SDF
别名 对羟基苯甲酸
化学名 4-hydroxybenzoic acid
Canonical SMILES OC1=CC=C(C(O)=O)C=C1
分子式 C7H6O3 分子量 138.12
溶解度 ≥ 13.8mg/mL in DMSO 储存条件 Store at -20°C
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1 mg 5 mg 10 mg
1 mM 7.2401 mL 36.2004 mL 72.4008 mL
5 mM 1.448 mL 7.2401 mL 14.4802 mL
10 mM 0.724 mL 3.62 mL 7.2401 mL
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