4-Methoxyphenyl-β-D-Glucopyranoside

4-Methoxyphenyl-β-D-glucopyranoside is an aryl glycoside that has been found in Pterospermum heterophyllum roots and has ice recrystallization inhibitory activity.¹,² It reduces mean grain size in a cell-free ice recrystallization assay and increases the percentage of intact isolated red blood cells (RBCs) in PBS post-freeze-thaw when used at a concentration of 100 mM.² 4-Methoxyphenyl-β-D-glucopyranoside has also been used as an intermediate in the synthesis of glucan oligosaccharides.³

1.Wang, M.-M., Li, S., Luo, G.-M., et al.Chemical constituents from roots of Pterospermum heterophyllumZhongcaoyao43(9)1699-1703(2012) 2.Briard, J.G., Poisson, J.S., Turner, T.R., et al.Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawingSci. Rep.6(1)23619(2016) 3.Montel, E., Hrmova, M., Fincher, G.B., et al.A chemoenzymatic route to conjugatable β(1→3)-glucan oligosaccharidesAus. J. Chem.62(6)575-584(2009)