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5-hydroxy Indole-3-acetic Acid-d6 Sale

(Synonyms: 5-HIAA-d6, 5-Hydroxyindoleacetic Acid-d6, 5-hydroxy IAA-d6) 目录号 : GC52172

An internal standard for the quantification of 5-hydroxy indole-3-acetic acid

5-hydroxy Indole-3-acetic Acid-d6 Chemical Structure

Cas No.:2748469-82-9

规格 价格 库存 购买数量
500 µg
¥872.00
现货
1 mg
¥1,571.00
现货
5 mg
¥5,234.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

5-hydroxy Indole-3-acetic acid-d6 (5-HIAA-d6) is intended for use as an internal standard for the quantification of 5-HIAA by GC- or LC-MS. 5-HIAA is a metabolite of the monoamine neurotransmitter serotonin .1 It is formed from serotonin via a 5-hydroxy indole-3-acetaldehyde intermediate by aldehyde dehydrogenase. 5-HIAA has been used as a biomarker for the detection of neuroendocrine tumors. Brain levels of 5-HIAA are decreased in patients with severe Alzheimer's disease.2

1.Corcuff, J.-B., Chardon, L., El Hajji Ridah, I., et al.Urinary sampling for 5HIAA and metanephrines determination: Revisiting the recommendationsEndocr. Connect.6(6)R87-R98(2017) 2.Vermeiren , Y., Van Dam, D., Aerts, T., et al.Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's diseaseNeurobiol. Aging35(12)2691-2700(2014)

Chemical Properties

Cas No. 2748469-82-9 SDF Download SDF
别名 5-HIAA-d6, 5-Hydroxyindoleacetic Acid-d6, 5-hydroxy IAA-d6
Canonical SMILES OC(C([2H])([2H])C(C1=C2[2H])=C([2H])NC1=C([2H])C([2H])=C2O)=O
分子式 C10H3D6NO3 分子量 197.2
溶解度 DMSO: soluble,Ethyl Acetate: soluble,Methanol: soluble 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 5.071 mL 25.355 mL 50.7099 mL
5 mM 1.0142 mL 5.071 mL 10.142 mL
10 mM 0.5071 mL 2.5355 mL 5.071 mL
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