9(S)-Hexahydrocannabinol-d9
(Synonyms: 9α-Hexahydrocannabinol-d9,11α-Hexahydrocannabinol-d9,9α-HHC-d9,9(S)-HHC-d9,11α-HHC-d9,trans-(6aR,9S,10aR)-HHC-d9) 目录号 : GC917319(S)-Hexahydrocannabinol-d9 is intended for use as an internal standard for the quantification of 9(S)-hexahydrocannabinol by GC- or LC-MS.
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
9(S)-Hexahydrocannabinol-d9 is intended for use as an internal standard for the quantification of 9(S)-hexahydrocannabinol by GC- or LC-MS. 9(S)-Hexahydrocannabinol is structurally similar to known phytocannabinoids.[1] It induces drowsiness, decreased motor activity, occasional partial ptosis, and occasional head drop, markers of psychotropic activity, in rhesus monkeys.[2] This product is intended for research and forensic applications.
References:
[1].Lee, Y.R., and Xia, L.Efficient one-pot synthetic approaches for cannabinoid analogues and their application to biologically interesting (–)-hexahydrocannabinol and (+)-hexahydrocannabinolTetrahedron Lett.49(20)3283-3287(2008).
[2].Mechoulam, R., Lander, N., Varkony, T.H., et al.Stereochemical requirements for cannabinoid activityJ. Med. Chem.23(10)1068-1072(1980).
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.0722 mL | 15.361 mL | 30.722 mL |
5 mM | 0.6144 mL | 3.0722 mL | 6.1444 mL |
10 mM | 0.3072 mL | 1.5361 mL | 3.0722 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。