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β-defesin 1 (pig) (TFA)

目录号 : GC72141

β-defesin 1 (pig) (TFA)是一种来自猪组织的内源性组成性表达的抗菌肽(AMP),尤其在猪粘膜上皮部位表达。

β-defesin 1 (pig) (TFA) Chemical Structure

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1 mg
¥3,690.00
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Sample solution is provided at 25 µL, 10mM.

Description

β-defesin 1 (pig) (pBD-1) TFA is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) TFA has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs.

In a northern blot analysis, β-defesin 1 (pig) TFA mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs[1].
In RT-PCR analysis, β-defesin 1 (pig) TFA message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express β-defesin 1 (pig) TFA are peripheral blood mononuclear cells[1].

References:
[1]. Zhang G, et al. Molecular cloningandtissueexpressionofporcinebeta-defensin-1.FEBS Lett.1998 Mar 6;424(1-2):37-40.

化学性质

Cas No. SDF
分子式 C180H313N59O50S9.10C2HF3O2 分子量 5532.56
溶解度 DMSO : 100 mg/mL (18.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO); H2O : 25 mg/mL (4.52 mM; Need ultrasonic) 储存条件 Sealed storage, away from moisture and light
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.1807 mL 0.9037 mL 1.8075 mL
5 mM 0.0361 mL 0.1807 mL 0.3615 mL
10 mM 0.0181 mL 0.0904 mL 0.1807 mL
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