AARS Human
目录号 : GP21322Alanyl-tRNA Synthetase Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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AARSHuman Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 107,598 Dalton. AARSis expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
| Purity | AARS purity is greater than 90% as determined by SDS-PAGE. | Source | Sf9 insect cells. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Alanyl-tRNA synthetase cytoplasmic; EC 6.1.1.7; Alanine-tRNA ligase; AlaRS; Renal carcinoma antigen NY-REN-42; PL-12; AARS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles. | ||
| Formulation | AARSis supplied in16mM HEPES buffer pH-8, 250mM sodium chloride, and 20% glycerol. | ||
Alanyl-tRNA synthetase is a member of the aminoacyl-tRNA synthetase family, key enzymes of protein biosynthesis which charge tRNA molecules with the respective amino acids. This 108 kDa protein is an autoantigen recognized by PL-12 antibodies which occur in a subset of patients with polymyositis and dermatomyositis. Preliminary data suggest that epitope spreading occurs in the autoimmune PL-12 response such that even antibodies to an isolated alanyl-tRNA molecule can develop.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.