Activin-A Human, HEK-Active
目录号 : GP20003Activin-A Human Recombinant, HEK-Active
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95% as obsereved by SDS-PAGE. | Source | HEK. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Inhba; Inhibin beta A; FSH releasing protein. | ||
| Solubility | It is recommended to reconstitute the lyophilized Activin-A in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized Activin-A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Activin-A should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line) and is typically 0.5-5ng/ml. | ||
| Formulation | The Activin-A was lyophilized from 1mg/ml in 1xPBS. | ||
Activins are homodimers or heterodimers of the different ж┬ subunit isoforms, part of the TGFж┬ family. Mature Activin A has two 116 amino acids residues ж┬A subunits (ж┬A-ж┬A). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.
The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line) and is typically 0.5-5ng/ml.
Lyophilized Activin-A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Activin-A should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.