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ACVRL1 Human

目录号 : GP20010

Activin A Receptor Type II-Like 1 Human Recombinant

ACVRL1 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

ACVRL1 produced in Sf9 Insect cells is a single, glycosylatedpolypeptide chain containing 103 amino acids (22-118a.a.) and having amolecular mass of 11.5kDa. (Molecular size on SDS-PAGE will appear atapproximately 18-28kDa).ACVRL1 is expressed with a 6 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 95.0% as determined by SDS-PAGE. Source Sf9,Insect cells.
Phycical Appearance Sterilefiltered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Activin A Receptor Type II-Like 1; ACVRLK1; ALK1; TGF-BSuperfamily Receptor Type I EC 2.7.11.30; TSR-I; ALK-1; HHT2; SKR3Serine/Threonine-Protein Kinase Receptor R3 Activin A Receptor; TypeII-Like Kinase 1; Activin Receptor-Like Kinase 1; EC 2.7.11; ORW2; HHT.
Amino Acid Sequence DPVKPSRGPL VTCTCESPHC KGPTCRGAWC TVVLVREEGR HPQEHRGCGN LHRELCRGRP TEFVNHYCCD SHLCNHNVSL VLEATQPPSE
Stability Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation ACVRL1 protein solution (0.25mg/ml) contains phosphatebuffered saline (pH7.4) and 10% glycerol.

Introduction

Activin A Receptor Type II-Like 1, also knownas ACVRL1 is a membrane-anchored proteoglycan which his core protein binds TGFf3 and has a shortcytoplasmic domain with no discernible signaling structure. Furthermore, ACVRL1 shares similar domain structures withother closely related ALK or activin receptor-like kinase proteins which form asubfamily of receptor serine/threonine kinases.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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