AKR1A1 Human
目录号 : GP21373Aldo-Keto Reductase Family 1 Member A1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Alcohol dehydrogenase; ALR; ARM; DD3; ALDR1; MGC1380; MGC12529; AKR1A1; Alcohol dehydrogenase [NADP+]; Aldehyde reductase; Aldo-keto reductase family 1 member A1. | ||
Amino Acid Sequence | MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE PVVLALAEKY GRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY. | ||
Stability | AKR1A1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles. | ||
Formulation | AKR1A1 solution containing 20mM Tris pH-8, 50mM NaCl and 10% glycerol. |
AKR1A1 is part of the aldo/keto reductase superfamily, it catalyzes the NADPH-dependent reduction from a range of aromatic and aliphatic aldehydes to their related alcohols. AKR1A1 corresponds (65% identity) to aldose reductase, an enzyme that takes part in the pathogenesis of some diabetic and galactosemic complications. AKR1A1 is involved in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs.
AKR1A1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C . Please prevent freeze thaw cycles.