all-cis-4,7,10,13,16-Docosapentaenoic Acid
(Synonyms: 二十二碳五烯酸) 目录号 : GC40812A polyunsaturated ω-6 fatty acid
Cas No.:25182-74-5
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as osbond acid, is an isomer of DPA. It is an ω-6 fatty acid formed by the elongation and desaturation of arachidonic acid . Levels of this fatty acid may be diminished during fatty acid desaturase syndrome and this may affect development. Upregulated expression of hepatic elongation of very long fatty acids protein 6 and increased levels of very long chain fatty acids, including all-cis-4,7,10,13,16-DPA, are characteristic of non-alcoholic steatohepatitis, a preneoplastic condition of hepatocellular carcinoma.
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.0257 mL | 15.1286 mL | 30.2572 mL |
5 mM | 0.6051 mL | 3.0257 mL | 6.0514 mL |
10 mM | 0.3026 mL | 1.5129 mL | 3.0257 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。