Andecaliximab

(Synonyms: Anti-MMP9 Reference Antibody (andecaliximab)) 目录号 : GC68656

Andecaliximab 是一种靶向基质金属蛋白酶 9 (MMP9) 的重组 IgG4 单克隆抗体。Andecaliximab 在特发性肺纤维化小鼠模型中显示出抗纤维化疗效。Andecaliximab 可用于胃腺癌和特发性肺纤维化 (IPF) 的研究。

Cas No.:1518996-49-0

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5mg ¥4,500.00 现货 0 1 2 3 4 5 6 7 8 9 10 10mg ¥7,200.00 现货 0 1 2 3 4 5 6 7 8 9 10 电话：400-920-5774 Email: sales@glpbio.cn 加 入 购 物 车 大 货 询 价				Customer Reviews Based on customer reviews. B1

Sample solution is provided at 25 µL, 10mM.

GlpBio产品文献引用

 

 

 

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Adv Funct Mater
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产品描述 化学性质 产品文档

Description

Andecaliximab is a recombinant chimeric Decreased SMAD2 phosphorylation and increased surfactant protein C. Reduced MMP9⁺ cells, including MMP9⁺, CCR10⁺ and MMP9⁺CD45^- and EpCAM⁺CCR10⁺ subpopulations.

[1]. Andrew E. Greenstein, et al. Effect of andecaliximab (anti-MMP9) on proteolysis of IL-7 in vitro, TCR diversity in mice, and serum IL-7 in gastric cancer patients in combination with chemotherapy. 2018 ASCO-SITC Clinical Immuno-Oncology Symposium.
[2]. Espindola MS, et al. Differential Responses to Targeting Matrix Metalloproteinase 9 in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 Feb 15;203(4):458-470.