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Anitrazafen (LY 122512) Sale

(Synonyms: 阿尼扎芬; LY 122512) 目录号 : GC31859

Annitrazafen (LY 122512) 是一种局部有效的抗炎剂。

Anitrazafen (LY 122512) Chemical Structure

Cas No.:63119-27-7

规格 价格 库存 购买数量
5mg
¥1,339.00
现货
10mg
¥1,874.00
现货
25mg
¥4,016.00
现货

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Sample solution is provided at 25 µL, 10mM.

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实验参考方法

Animal experiment:

Male albino rats (200 to 250 g) are fasted for 24 h before experiment. [3-14C]Anitrazafen (25 mg/kg) is administered orally to twelve rats. At specific times after dosing, three animals are killed by decapitation and samples of blood and appropriate tissues are removed. Duplicate weighed samples of blood and each tissue are removed for 14C assay[1].

References:

[1]. Sullivan HR, et al. Absorption and metabolism of anitrazafen, a topically effective anti-inflammatory agent, in the rat. Xenobiotica. 1981 Jan;11(1):9-22.

产品描述

Anitrazafen is a topically effective antiinflammatory agent.

Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3-14C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14C after subcutaneous administration of [3-14C]Anitrazafen in corn oil solution are about one half those found after oral administration[1].

[1]. Sullivan HR, et al. Absorption and metabolism of anitrazafen, a topically effective anti-inflammatory agent, in the rat. Xenobiotica. 1981 Jan;11(1):9-22.

Chemical Properties

Cas No. 63119-27-7 SDF
别名 阿尼扎芬; LY 122512
Canonical SMILES CC1=NC(C2=CC=C(OC)C=C2)=C(C3=CC=C(OC)C=C3)N=N1
分子式 C18H17N3O2 分子量 307.35
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.2536 mL 16.2681 mL 32.5362 mL
5 mM 0.6507 mL 3.2536 mL 6.5072 mL
10 mM 0.3254 mL 1.6268 mL 3.2536 mL
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