APOBEC4 Human
目录号 : GP22745Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 4 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Apolipoprotein B MRNA Editing Enzyme; CatalyticPolypeptide-Like 4 (Putative); C1orf169; Apolipoprotein B MRNA-Editing EnzymeCatalytic Polypeptide-Like 4; Chromosome 1 Open Reading Frame 169; Putative C->U-EditingEnzyme APOBEC-4; EC 3.5.4. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTEFCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRHIILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSGSHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSGQLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
Formulation | APOBEC4 protein solution (1mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol. |
APOBEC4belongs to the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases,which convert cytidine to uridine. Further AID/APOBEC family members areimplicated in Mrna editing, somatic hypermutation and recombination ofimmunoglobulin genes, and innate immunity to retroviral infection. Among thediseases associated with APOBEC4 are systemic lupus erythematosus, and lupuserythematosus.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.