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Apronal (Allylisopropylacetylurea) Sale

(Synonyms: 丙戊酰脲; Allylisopropylacetylurea; Apronalide) 目录号 : GC33737

A muscle relaxant

Apronal (Allylisopropylacetylurea) Chemical Structure

Cas No.:528-92-7

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥491.00
现货
100mg
¥446.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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实验参考方法

Animal experiment:

Rats: Apronal is administered to male Sandoz OFA-SPF rats, weighing 140-150 g in two equal daily subcutaneous injections 8 h apart. The overall daily dose is 400 mg/kg and dosing is continued for 21 days. Control rats are similarly treated with propandiol only. Urine samples are collected in glass tubes at solid CO2, temperatures and stored frozen until analysis[1].

References:

[1]. Rentsch G, et al. The effect of prolonged administration of allylisopropylacetylurea to rats on cytochrome P-450 and other liver haemoproteins. Xenobiotica. 1976 Mar;6(3):151-7.
[2]. Fujimoto Y, et al. Fixed drug eruption due to allylisopropylacetylurea. Contact Dermatitis. 1993 May;28(5):282-4.

产品描述

Apronal is a muscle relaxant.1 It prolongs methylhexabital-induced sleep and enhances morphine-induced analgesia in dogs, mice, and rats. Apronal has been used to induce experimental porphyria in rabbits.2 Formulations containing apronal have previously been used as daytime sedatives.

1.Yajima, T., Uritani, K., Aoki, R., et al.Pharmacological studies on allylisopropylacetylurea (apronalide), a drug with central nervous system activityOyo Yakuri11(5)693-717(1976) 2.Schmid, R.M., and Schwartz, S.Experimental porphyria. III. Hepatic type produced by sedormidProc. Soc. Exp. Biol. Med.81(3)685-689(1952)

Chemical Properties

Cas No. 528-92-7 SDF
别名 丙戊酰脲; Allylisopropylacetylurea; Apronalide
Canonical SMILES C=CCC(C(C)C)C(NC(N)=O)=O
分子式 C9H16N2O2 分子量 184.24
溶解度 DMSO : ≥ 165 mg/mL (895.57 mM) 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 5.4277 mL 27.1385 mL 54.277 mL
5 mM 1.0855 mL 5.4277 mL 10.8554 mL
10 mM 0.5428 mL 2.7139 mL 5.4277 mL
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