Aprotinin Protein
目录号 : GP22752Aprotinin
Sample solution is provided at 25 µL, 10mM.
Purity | Source | Bovine Lung. | |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | Pancreatic trypsin inhibitor; Basic protease inhibitor; BPI; BPTI; Aprotinin; AP. | ||
Solubility | It is recommended to reconstitute the lyophilized Aprotinin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
Stability | Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Aprotinin should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
Formulation | The protein (1mg/ml) was lyophilized with no additives. |
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Aprotinin should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.