Azadirachtin
(Synonyms: 印楝素) 目录号 : GC46901
A naturally-occurring insecticide
Cas No.:11141-17-6
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Azadirachtin is a naturally-occurring insecticide originally isolated from the seeds of A. indica.1 It inhibits feeding behavior, molting, and/or ovarian development in a species-dependent manner in insects.2 Azadirachtin inhibits feeding on G. barbadense leaves and cotyledon disks by third instar H. zea larvae with protection concentrations (PC95s) of 6.2 and 6.8 μg/disk, respectively.3 It inhibits ecdysis and growth of H. zea, H. virescens, S. frugiperda, and P. gossypiella with ecdysis inhibition values (EI95s) ranging from 1 to 10 ppm and ED50 values ranging from 0.4 to 0.7 ppm. Azadirachtin inhibits the growth of freshly molted fourth instar E. varivestis larva (LC50 = 1.66 ppm).2 It is lethal to A. stephensi first, second, third, and fourth instar larva, pupa, and adults at a concentration of 0.1 ppm.4
1.Butterworth, J.H., and Morgan, E.D.Isolation of a substance that suppresses feeding in locustsChem. Commun. (Lond.)123-24(1968) 2.Rembold, H.Azadirachtins. Their structure and mode of actionInsecticides of Plant Origin150-163(1989) 3.Kubo, I., and Kocke, J.A.Azadirachtin, insect ecdysis inhibitorAgr. Biol. Chem.46(7)1951-1953(1982) 4.Nathan, S.S., Kalaivani, K., and Murugan, K.Effects of neem limonoids on the malaria vector Anopheles stephensi Liston (Diptera: Culicidae)Acta. Trop.96(1)47-55(2005)
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 1.3875 mL | 6.9377 mL | 13.8754 mL |
| 5 mM | 0.2775 mL | 1.3875 mL | 2.7751 mL |
| 10 mM | 0.1388 mL | 0.6938 mL | 1.3875 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。