BD 3 Rat
目录号 : GP20080Beta Defensin-3 Rat Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Beta-defensin 3; BD-3; Defensin beta 3; Defb3. | ||
| Amino Acid Sequence | KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K. | ||
| Solubility | It is recommended to reconstitute the lyophilized BD-3 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized BD-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | ||
| Biological Activity | Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20µg/ml, corresponding to a specific activity of 50,000-250,000units/mg. | ||
| Formulation | BD-3 protein was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. | ||
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20µg/ml, corresponding to a specific activity of 50,000-250,000units/mg.
Lyophilized BD-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BD-3 should be stored at 4°C between 2-7 days and for future use below -18°C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.