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BEX1 Human

目录号 : GP22872

Brain Expressed X-Linked 1 Human Recombinant

BEX1 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

BEX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 148 amino acids (1-125) and having a molecular mass of 17.2kDa. BEX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 80% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms BEX2; HBEX2; HGR74-h; Protein BEX1; Brain-expressed X-linked protein 1.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMESKEKR AVNSLSMENA NQENEEKEQV ANKGEPLALP LDAGEYCVPR GNRRRFRVRQ PILQYRWDMM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation The BEX1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.

Introduction

Brain Expressed X-Linked 1 (BEX1) which participates in cell cycle progression and neuronal differentiation, is a signaling adapter molecule involved in p75NTR/NGFR signaling. BEX1 inhibits neuronal differentiation in response to nerve growth factor. BEX1 links between the cell cycle and neurotrophic factor signaling by acting as an upstream modulator of receptor signaling, adjusting biological responses to external signals with internal cellular states.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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