BMP 2 Human, HEK
目录号 : GP20099Bone Morphogenetic protein-2 Human Recombinant, HEK
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 95.0% as determined by analysis by SDS-PAGE. | Source | HEK. |
Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
Synonyms | BMP-2; BMP2A. | ||
Amino Acid Sequence | QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNST NHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR. | ||
Solubility | It is recommended to reconstitute the lyophilized BMP-2 in sterile 4mM HCl containing 0.1% endotoxin-free recombinant HSA. | ||
Stability | Lyophilized BMP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BMP-2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
Biological Activity | The specific activity as determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) was found to be 6.53ng/ml. | ||
Formulation | The BMP2 was lyophilized from 0.67mg/ml in 2xPBS + 6% ethanol. |
BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva.
The specific activity as determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) was found to be 6.53ng/ml.
Lyophilized BMP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution BMP-2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.