Buccalin A (trifluoroacetate salt)
目录号 : GC91837Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling.[1] It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10 nM. Buccalin A (10 µM) decreases the amplitude of inhibitory post-synaptic currents (IPSCs) in isolated and perfused voltage-clamped A. californica buccal ganglia.[2]
References:
[1].Cropper, E.C., Miller, M.W., Tenenbaum, R., et al.Structure and action of buccalin: A modulatory neuropeptide localized to an identified small cardioactive peptide-containing cholinergic motor neuron of Aplysia californicaProc. Natl. Acad. Sci. USA85(16)6177-6181(1988).
[2].Baux, G., Fossier, P., Trudeau, L.E., et al.Transmitter release and calcium currents at an Aplysia buccal ganglion synapse--II. Modulation by presynaptic receptorsNeuroscience53(2)581-593(1993).
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 0.9495 mL | 4.7474 mL | 9.4949 mL |
| 5 mM | 0.1899 mL | 0.9495 mL | 1.899 mL |
| 10 mM | 0.0949 mL | 0.4747 mL | 0.9495 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。