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Butylparaben (Butyl parahydroxybenzoate) Sale

(Synonyms: 对羟基苯甲酸丁酯; Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate) 目录号 : GC32255

A paraben

Butylparaben (Butyl parahydroxybenzoate) Chemical Structure

Cas No.:94-26-8

规格 价格 库存 购买数量
5g
¥77.00
现货
10g
¥123.00
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25g
¥245.00
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Sample solution is provided at 25 µL, 10mM.

Description

Butyl 4-hydroxybenzoate is a paraben that has been found in Microbulbifer.1 It is active against the Gram-positive bacteria B. subtilis and S. aureus, yeast C. molischiana and S. cerevisiae, and fungi A. niger and P. chrysogenum (MICs = 75, 75, 60, 52, 55, and 45 mg/L, respectively). Butyl 4-hydroxybenzoate (300-1,000 ?M) decreases the viability of, and ATP and glutathione (GSH) levels in, HepG2 and human dermal fibroblast neonatal (HDFn) cells.2 It binds to estrogen receptors in a concentration-dependent manner and increases uterine weight in immature and ovariectomized rats.3 Butyl 4-hydroxybenzoate has been found in influent and effluent wastewater.4 Formulations containing butyl 4-hydroxybenzoate have been used as preservatives in cosmetics, food, and pharmaceuticals.

1.Peng, X., Adachi, K., Chen, C., et al.Discovery of a marine bacterium producing 4-hydroxybenzoate and its alkyl esters, parabensAppl. Environ. Microbiol.72(8)5556-5561(2006) 2.Kizhedath, A., Wilkinson, S., and Glassey, J.Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro modelsToxicol. In Vitro55108-115(2019) 3.Routledge, E.J., Parker, J., Odum, J., et al.Some alkyl hydroxy benzoate preservatives (parabens) are estrogenicToxicol. Appl. Pharmacol.153(1)12-19(1998) 4.Wang, W., and Kannan, K.Fate of parabens and their metabolites in two wastewater treatment plants in New York state, United StatesEnviron. Sci. Technol.50(3)1174-1181(2016)

化学性质

Cas No. 94-26-8 SDF
别名 对羟基苯甲酸丁酯; Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate
Canonical SMILES O=C(OCCCC)C1=CC=C(O)C=C1
分子式 C11H14O3 分子量 194.23
溶解度 Insoluble in Water; ≥116.2 mg/mL in DMSO; ≥47.2 mg/mL in EtOH 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 5.1485 mL 25.7427 mL 51.4854 mL
5 mM 1.0297 mL 5.1485 mL 10.2971 mL
10 mM 0.5149 mL 2.5743 mL 5.1485 mL
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