C1GALT1 Human
目录号 : GP21450Core 1 Beta3-Gal-T1 人类重组体
Sample solution is provided at 25 µL, 10mM.
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C1GALT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (30-363 a.a) and having a molecular mass of 41.4kDa.
| Purity | Greater than 80.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Core 1 Synthase; Glycoprotein-N-Acetylgalactosamine3-Beta-Galactosyltransferase 1; Core 1 Beta3-Gal-T1; Core 1 O-Glycan T-Synthase;Core 1 UDP-Galactose:N-Acetylgalactosamine-Alpha-R Beta 1;3 Galactosyltransferase1; B3Gal-T8; EC 2.4.1.122; Core 1 Beta3-Gal-T; C1GALT; T-synthase; Glycoprotein-N-Acetylgalactosamine3-Beta-Galactosyltransferase 1; Beta-1;3-galactosyltransferase; C1GalT1; Core 1Beta1;3-Galactosyltransferase 1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSLLGEKVD TQPNVLHNDP HARHSDDNGQ NHLEGQMNFN ADSSQHKDEN TDIAENLYQK VRILCWVMTG PQNLEKKAKH VKATWAQRCN KVLFMSSEEN KDFPAVGLKT KEGRDQLYWK TIKAFQYVHE HYLEDADWFL KADDDTYVIL DNLRWLLSKY DPEEPIYFGR RFKPYVKQGY MSGGAGYVLS KEALKRFVDA FKTDKCTHSS SIEDLALGRC MEIMNVEAGD SRDTIGKETF HPFVPEHHLI KGYLPRTFWY WNYNYYPPVE GPGCCSDLAV SFHYVDSTTM YELEYLVYHL RPYGYLYRYQ PTLPERILKE ISQANKNEDT KVKLGNP. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | C1GALT1 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. | ||
Core1 Beta3-Gal-T1 also known as, C1GALT1 creates the common core 1 O-glycanstructure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal toGalNAc-alpha-1-R. Core 1 is a precursor for lots of extended mucin-typeO-glycans on cell surfaceand secreted glycoproteins. Studies in mice have shown that this gene takes amain role in angiogenesis, thrombopoiesis and kidney homeostasis.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.