C9ORF95 Human
目录号 : GP22946Chromosome 9 Open Reading Frame 95 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Nicotinamide riboside kinase 1; NRK 1; NmR-K 1; Nicotinic acid riboside kinase 1; Ribosylnicotinamide kinase 1; RNK 1; Ribosylnicotinic acid kinase 1; NMRK1; C9orf95; NRK1; bA235O14.2; RP11-235O14.2. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMKTFIIG ISGVTNSGKT TLAKNLQKHL PNCSVISQDD FFKPESEIET DKNGFLQYDV LEALNMEKMM SAISCWMESA RHSVVSTDQE SAEEIPILII EGFLLFNYKP LDTIWNRSYF LTIPYEECKR RRSTRVYQPP DSPGYFDGHV WPMYLKYRQE MQDITWEVVY LDGTKSEEDL FLQVYEDLIQ ELAKQKCLQV TA. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | C9ORF95 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT and 200mM NaCl. |
Chromosome 9 Open Reading Frame 95 (C9ORF95/NRK1) is a member of the uridine kinase family. NAD+ is vital for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in countless reactions, including those which delay aging in experimental systems. Nicotinic acid and nicotinamide are defined as the vitamin precursors of NAD+. C9ORF95 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). C9ORF95 also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.