CAMLG Human
目录号 : GP22963Calcium Modulating Ligand Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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CAMLG Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-189) and having a molecular mass of 23.2kDa.
| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Calcium Modulating Ligand; Calcium-Modulating Cyclophilin Ligand; Calcium-Signal Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein; CAML. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMESMAVA TDGGERPGVP AGSGLSASQR RAELRRRKLL MNSEQRINRI MGFHRPGSGA EEESQTKSKQ QDSDKLNSLS VPSVSKRVVL GDSVSTGTTD QQGGVAEVKG TQLGDKLDSF IKPPECSSDV NLELRQRNRG DLTADSVQRG SRHGLEQYLS RFEEAMKLRK QLISEKPSQE DGNTTEEFDS FR | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
| Formulation | The CAMLG solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol. | ||
CAMLG binds to cyclophilin B and operates downstream of the TCR and upstream of calcineurin by causing an influx of calcium. CAMLG is an essential membrane protein that takes part in the calcium signal transduction pathway, connecting cyclophilin B to calcium signaling.
Store at 4°C if entire vial will be used within 2-4 weeks.