CASQ2 Dog
目录号 : GP23298Calsequestrin-2 Dog
Sample solution is provided at 25 µL, 10mM.
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Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40-50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Dog Heart. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Calsequestrin-2; Calsequestrin cardiac muscle isoform; CASQ2; CSQ. | ||
| Solubility | It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Formulation | The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA. | ||
Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution CASQ2 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.