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CCBL1 Human

目录号 : GP21470

Cysteine Conjugate-Beta Lyase Cytoplasmic Human Recombinant

CCBL1 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

Description

CCBL1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 445 amino acids (1-422 a.a) andhaving a molecular mass of 50.3kDa.CCBL1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Cysteine Conjugate-Beta Lyase; Cytoplasmic; GlutamineTransaminase K; Cysteine Conjugate-Beta Lyase; Cytoplasmic (GlutamineTransaminase K; Kyneurenine Aminotransferase); Kynurenine--OxoglutarateTransaminase I; Glutamine--Phenylpyruvate Transaminase; Cysteine-S-ConjugateBeta-Lyase; Kynurenine Aminotransferase I; Kyneurenine Aminotransferase; KATI; GTK;Glutamine-Phenylpyruvate Aminotransferase; Kynurenine--OxoglutarateTransaminase 1; Beta-Lysase; Kidney; EC 4.4.1.13; EC 2.6.1.64; EC 2.6.1.7; KAT1;Kynurenine--oxoglutarate transaminase 1.
Amino Acid Sequence MGSSHHHHHHSSGLVPRGSH MGSMAKQLQARRLDGIDYNP WVEFVKLASE HDVVNLGQGF PDFPPPDFAV EAFQHAVSGD FMLNQYTKTF GYPPLTKILASFFGELLGQE IDPLRNVLVT VGGYGALFTA FQALVDEGDE VIIIEPFFDC YEPMTMMAGG RPVFVSLKPGPIQNGELGSS SNWQLDPMEL AGKFTSRTKA LVLNTPNNPL GKVFSREELE LVASLCQQHD VVCITDEVYQWMVYDGHQHI SIASLPGMWE RTLTIGSAGK TFSATGWKVG WVLGPDHIMK HLRTVHQNSV FHCPTQSQAAVAESFEREQL LFRQPSSYFV QFPQAMQRCR DHMIRSLQSV GLKPIIPQGS YFLITDISDF KRKMPDLPGAVDEPYDRRFV KWMIKNKGLV AIPVSIFYSV PHQKHFDHYI RFCFVKDEAT LQAMDEKLRK WKVEL.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CCBL1 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4), 10% glycerol and 1mM DTT.

Introduction

Cysteine Conjugate-Beta Lyase Cytoplasmic also known as CCBL1 is a member of the class-I pyridoxal-phosphate-dependent aminotransferase family. CCBL1 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA) it also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Furthermore, CCBL1 catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno) cysteine, resulting in the cleavage of the C-S or C-Se bond.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

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