CD1E Human
目录号 : GP23001CD1E Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | CD1A; R2; T-cell surface glycoprotein CD1e; membrane-associated; R2G1; sCD1e. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLKPWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFLSFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCGPSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVKHSSLGGHDLI IHWGGYS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | CD1E protein solution (1mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol and 0.4M Urea. | ||
CD1E belongs to the CD1family of transmembrane glycoproteins which are structurally associated to the mainMHC (histocompatibility complex) proteins and form heterodimers withbeta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipidand glycolipid antigens of self or microbial origin to T cells. The humangenome is comprised of 5 CD1 family genes organized in a cluster on chromosome1. The CD1 family members are belief to differ in their cellular localizationand specificity for particular lipid ligands. CD1E localizes within Golgicompartments, endosomes, and lysosomes, and is cleaved into a steady solubleform. The soluble form is necessary for the intracellular processing of someglycolipids into a form that can be presented by other CD1 family members.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.