CD4 Human (26-226)
目录号 : GP20867CD-4 (26-226 a.a.) Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Source | Escherichia Coli. | |
Phycical Appearance | Sterile filtered liquid. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | gp55; HLA-2; L3 / T4; Ly-4; T cell antigen T4/LEU3; T4; sCD4. | ||
Stability | Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles. | ||
Formulation | Recombinant Human protein at 100µg/ml in 50mM Tris-HCl, (pH-7.5) and 10mM L-glutathione. |
CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.