CD47 Human
目录号 : GP23025CD47 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Sf9, Baculovirus cells. |
Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | CD47 Molecule; Antigenic Surface Determinant Protein OA3; CD47 Antigen (Rh-Related Antigen; Integrin-Associated Signal Transducer); Antigen Identified By Monoclonal Antibody 1D8; Integrin Associated Protein; Integrin-Associated Protein; Rh-Related Antigen; CD47 Glycoprotein; MER6; IAP; Integrin-Associated Signal Transducer; Leukocyte Surface Antigen CD47; CD47 Antigen; Protein MER6; OA3; CD47. | ||
Amino Acid Sequence | QLLFNKTKSV EFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASL KMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PNEHHHHHH. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | CD47 protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol. |
CD47, functions in cell adhesions by performing as an adhesion receptorfor THBS1 on platelets, furthermore CD47 plays a role in the modulation ofintegrins. In addition, CD47 takes a vital part in memory formation as well assynaptic plasticity in the hippocampus. Receptor for SIRPA avoids maturation ofimmature dendritic cells and inhibits cytokine production by mature dendriticcells. CD47 prevents premature elimination of red blood cells, and it is also implicatedin membrane permeability changes induced following virus infection.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.