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CD47 Human

目录号 : GP23025

CD47 Human Recombinant

CD47 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

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产品描述

CD47 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-141 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 129 amino acids and having a molecular mass of 14.7kDa.CD47 shows multiple bands between 18-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms CD47 Molecule; Antigenic Surface Determinant Protein OA3; CD47 Antigen (Rh-Related Antigen; Integrin-Associated Signal Transducer); Antigen Identified By Monoclonal Antibody 1D8; Integrin Associated Protein; Integrin-Associated Protein; Rh-Related Antigen; CD47 Glycoprotein; MER6; IAP; Integrin-Associated Signal Transducer; Leukocyte Surface Antigen CD47; CD47 Antigen; Protein MER6; OA3; CD47.
Amino Acid Sequence QLLFNKTKSV EFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASL KMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PNEHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CD47 protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol.

Introduction

CD47, functions in cell adhesions by performing as an adhesion receptorfor THBS1 on platelets, furthermore CD47 plays a role in the modulation ofintegrins. In addition, CD47 takes a vital part in memory formation as well assynaptic plasticity in the hippocampus. Receptor for SIRPA avoids maturation ofimmature dendritic cells and inhibits cytokine production by mature dendriticcells. CD47 prevents premature elimination of red blood cells, and it is also implicatedin membrane permeability changes induced following virus infection.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.