Cefmetazole sodium (Sodium cefmetazole)
(Synonyms: 头孢美唑钠; Sodium cefmetazole) 目录号 : GC32168A cephamycin antibiotic
Cas No.:56796-39-5
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Cefmetazole is a cephamycin antibiotic.1 It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 μg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.2
1.Jones, R.N., Barry, A.L., Fuchs, P.C., et al.Antimicrobial activity of cefmetazole (CS-1170) and recommendations of susceptibility testing by disk diffusion, dilution, and anaerobic methodsJ. Clin. Microbiol.24(6)1055-1059(1986) 2.Baker-Zander, S.A., and Lukehart, S.A.Efficacy of cefmetazole in the treatment of active syphilis in the rabbit modelAntimicrob. Agents Chemother.33(9)1465-1469(1989)
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 2.0263 mL | 10.1313 mL | 20.2626 mL |
5 mM | 0.4053 mL | 2.0263 mL | 4.0525 mL |
10 mM | 0.2026 mL | 1.0131 mL | 2.0263 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。