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Cefoselis hydrochloride Sale

(Synonyms: 盐酸头孢噻利) 目录号 : GC16076

盐酸头孢塞利斯是第四代头孢菌素,是一种β-内酰胺类抗生素。

Cefoselis hydrochloride Chemical Structure

Cas No.:911212-25-4

规格 价格 库存 购买数量
50mg
¥494.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Cefoselis is a widely used beta-lactam antibiotic.Target: AntibacterialCefoselis, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. The activity of Cefoselis was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis.Cefoselis was highly active against MSSA and MSCNS. Cefoselis was poor in the activity against MRSA,MRCNS,PRSP and Enterococcus faecalis,and no activity for Enterococcus faecium.

References:
[1]. King, A., L. Bethune, and I. Phillips, The Comparative In Vitro Activity of FK-037 (Cefoselis), a New Broad-Spectrum Cephalosporin. Clin Microbiol Infect, 1995. 1(1): p. 13-17.
[2]. ZHU, D., et al., In vitro activities of cefoselis compared to β-lactams and other antibacterial agents aganst gram-positive and gram-negative clinical isolates. Chinese Journal of Infection and Chemotherapy, 2011. 4: p. 002.

Chemical Properties

Cas No. 911212-25-4 SDF
别名 盐酸头孢噻利
化学名 (6R,7R)-7-((Z)-((Z)-1-hydroxy-2-(2-imino-2,3-dihydrothiazol-4-yl)-2-(methoxyimino)ethylidene)amino)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydro-1H-pyrazol-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
Canonical SMILES CO/N=C(\C(O)=N\[C@]([C@]1([H])N2C(C(O)=O)=C(CS1)CN3C=C/C(N3CCO)=N/[H])([H])C2=O)C(N4)=CSC4=N.Cl
分子式 C19H23ClN8O6S2 分子量 559.02
溶解度 Soluble in DMSO 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.7888 mL 8.9442 mL 17.8884 mL
5 mM 0.3578 mL 1.7888 mL 3.5777 mL
10 mM 0.1789 mL 0.8944 mL 1.7888 mL
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