CENPM Human
目录号 : GP23123Centromere Protein-M Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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CENPM Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (1-180) and having a molecular mass of 22.0kDa.
| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Centromere Protein M; Interphase Centromere Complex Protein 39; Chromosome 22 Open Reading Frame 18; Proliferation Associated Nuclear Element 1; bK250D10.2; CENP-M; ICEN39; C22orf18; PANE1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSVLRPL DKLPGLNTAT ILLVGTEDAL LQQLADSMLK EDCASELKVH LAKSLPLPSS VNRPRIDLIV FVVNLHSKYS LQNTEESLRH VDASFFLGKV CFLATGAGRE SHCSIHRHTV VKLAHTYQSP LLYCDLEVEG FRATMAQRLV RVLQICAGHV PGVSALNLLS LLRSSEGPSL EDL | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
| Formulation | The CENPM solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 30% glycerol. | ||
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.
Store at 4°C if entire vial will be used within 2-4 weeks.